Listar por autor "Rodríguez-Caso, Carlos Francisco"
Mostrando ítems 1-8 de 8
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A bottom-up characterization of transfer functions for synthetic biology designs: lessons from enzymology
Carbonell-Ballesteros, Max; Durán-Nebreda, Salva; Montañez, Raúl; Macía, Javier; Rodríguez-Caso, Carlos Francisco
(Oxfrod University Press, 2014-12-16)
Within the field of synthetic biology, a rational design of genetic parts should include a causal understanding of their input-output responses-the so-called transfer function-and how to tune them. However, a commonly ... -
Biología 2.0: Búsqueda de los principios de computación celular a través de la Biología Sintética
Rodríguez-Caso, Carlos Francisco (2015-11-04)
La biología sintética es una disciplina de nueva formación que busca la consolidación de una ingeniería partiendo de la biología molecular. En esta charla se discuten las diferencias entre esta nueva aproximación y las ... -
Can a minimal replicating construct be identified as the embodiment of cancer?
Solé, Ricard V.; Valverde, Sergi; Rodríguez-Caso, Carlos Francisco; Sardanyés, Josep (Wiley, 2014-04)
Genomic instability is a hallmark of cancer. Cancer cells that exhibit abnormal chromosomes are characteristic of most advanced tumours, despite the potential threat represented by accumulated genetic damage. Carcinogenesis ... -
Can cell mortality determine division of labor in tissue organization?
Rodríguez-Caso, Carlos Francisco (Elsevier, 2014-06)
Tissue organization comes from the emergence of cell cooperation where cell homeostasis and function are per- formed as a trade-off of two excluding proliferative and differentiated cellular states. By introducing function ... -
Dealing with the genetic load in bacterial synthetic biology circuits: convergences with the Ohm's law.
Carbonell-Ballesteros, Max; García-Ramallo, Eva; Montañez, Raúl; Rodríguez-Caso, Carlos Francisco; Macía, Javier (2015)
Synthetic biology seeks to envision living cells as a matter of engineering. However, increasing evidence suggests that the genetic load imposed by the incorporation of synthetic devices in a living organism introduces a ... -
De la idea al negocio o ¿Cómo montar una startup biotecnológica?
Rodríguez-Caso, Carlos Francisco (2020-01-07)
En la sociedad actual es cada vez más común hablar de emprendimiento. Emprender es afrontar la incertidumbre del desarrollo de un proyecto que generalmente contiene una componente alta de innovación. Las habilidades ... -
Mathematical Modeling of Polyamine Metabolism in Mammals.
Rodríguez-Caso, Carlos Francisco; Montañez, Raúl; Cascante, Marta; Sánchez-Jiménez, Francisca María; Medina-Torres, Miguel Ángel (Elsevier, 2006)
Polyamines are considered as essential compounds in living cells, since they are involved in cell proliferation, transcription, and translation processes. Furthermore, polyamine homeostasis is necessary to cell survival, ... -
When metabolism meets topology: Reconciling metabolite and reaction networks.
Montañez, Raúl; Medina-Torres, Miguel Ángel; Solé, Ricard V.; Rodríguez-Caso, Carlos Francisco (Wiley, 2010)
The search for a systems-level picture of metabolism as a web of molecular interactions provides a paradigmatic example of how the methods used to characterize a system can bias the interpretation of its functional meaning. ...