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Listar por autor "Real-Navarrete, Luis Miguel"
Mostrando ítems 1-6 de 6
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A Functional Pipeline of Genome-Wide Association Data Leads to Midostaurin as a Repurposed Drug for Alzheimer’s Disease
Esteban-Martos, Alvaro; Brokate-Llanos, Ana María; Real-Navarrete, Luis Miguel; Melgar-Locatelli, Sonia; De Rojas, Itziar; Castro-Zavala, Adriana; Bravo-Romero, María José; Mañas-Padilla, María del Carmen; García-González, Pablo; Ruiz-Galdón, Maximiliano; Pacheco-Sánchez, Beatriz; Polvillo, Rocío; Rodriguez-de-Fonseca, Fernando; González, Irene; Castilla-Ortega, María Estela; Muñoz-Gómez, Manuel; Rivera, Patricia; Reyes-Engel, Armando; Ruiz, Agustín; Royo-Sánchez-Palencia, José Luis[et al.] (MDPI, 2023)Genome-wide association studies (GWAS) constitute a powerful tool to identify the different biochemical pathways associated with disease. This knowledge can be used to prioritize drugs targeting these routes, paving the ... -
Correction to: Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease.
Boza-Serrano, Antonio; Ruiz, Rocío; Sánchez-Varo, Raquel María; García-Revilla, Juan; Yang, Yiyi; Jiménez-Ferrer, Itzia; Paulus, Agnes; Wennström, Malin; Vilalta, Anna; Allendorf, David; Dávila-Cansino, José Carlos; Stegmayr, John; Jiménez, Sebastián; Roca-Ceballos, Maria A.; Navarro-Garrido, Victoria; Swanberg, Maria; Hsieh, Christine L; Real-Navarrete, Luis Miguel; Englund, Elisabeth; Linse, Sara; Leffler, Hakon; Nilsson, Ulf J.; Brown, Guy C; Gutiérrez-Pérez, Antonia; Vitorica, Javier; Venero, José Luis; Deierborg, Thomas[et al.] (Springer, 2023-02-15)Alzheimer's disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of amyloid beta (Aβ) peptide, fibrillary tangles of intraneuronal tau and microglial activation are ... -
Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease.
Boza-Serrano, Antonio; Ruiz, Rocio; Sánchez-Varo, Raquel María; García‑Revilla, Juan; Yang, Yiyi; Jiménez-Ferrer, Itzia; Paulus, Agnes; Wennström, Malin; Vilalta, Ana; Allendorf, David; Dávila-Cansino, José Carlos; Stegmayr, John; Jiménez, Sebastián; Roca-Ceballos, Maria A.; Navarro-Garrido, Victoria; Swanberg, Maria; Hsieh, Christine L.; Real-Navarrete, Luis Miguel; Englund, Elisabeth; Linse, Sara; Leffler, Hakon; Nilsson, Ulf J.; Gutiérrez-Pérez, Antonia; Vitorica, Javier; Venero, José Luis; Deierborg, Thomas[et al.] (Springer, 2019-04-20)Alzheimer's disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of amyloid beta (Aβ) peptide, fibrillary tangles of intraneuronal tau and microglial activation are ... -
Incidence of and factors associated with SARS-CoV-2 infection among people living with HIV in Southern Spain after one year of pandemic
Fernández-Fuertes, Marta; Corma-Gómez, Anaïs; Torres, Eva; Rodriguez-Pineda, Elena; Fuentes-López, Ana; Rincon, Pilar; Fernández, Nieves; García, Federico; Bernal, Samuel; Real-Navarrete, Luis Miguel; Macías, Juan; Pineda, Juan A.[et al.] (Wiley, 2021-08-17)Whether people living with HIV (PLWH) are at greater risk of acquiring SARS-CoV-2 infection is currently unknown. Prospective serologic studies may allow seroincidence analyses, where all infections are accurately identified. ... -
Incidence of recently acquired hepatitis C virus infection among HIV-infected patients in southern Spain.
González-Serna, A.; Macías, Juan; Palacios-Muñoz, María Rosario; Gómez Ayerbe, Cristina; Téllez-Rico, Francisco Javier; Rivero-Juárez, Antonio; Fernández, M.; Santos-González, Jesús Leandro; Real-Navarrete, Luis Miguel; González-Doménech, Carmen María; Gómez-Mateos, J.; Pineda, Juan Antonio; HEPAVIR study group[et al.] (2020-12-26)Objectives: Spain is close to HCV microelimination, so rates of recently acquired HCV infection (RAHC) should decrease. Nowadays, men who have sex with men (MSM) carry the highest risk of HCV acquisition. Our aim was to ... -
Mendelian Randomisation Confirms the Role of Y-Chromosome Loss in Alzheimer’s Disease Aetiopathogenesis in Men
García-González, Pablo; Rojas, Itziar de; Moreno-Grau, Sonia; Montrreal, Laura; Puerta, Raquel; Alarcón-Martín, Emilio; Quintela, Inés; Orellana, Adela; Andrade, Victor; Martino Adami, Pamela V.; Heilmann-Heimbach, Stefanie; Gómez-Garre, Pilar; Periñán, María Teresa; Alvarez, Ignacio; Díez-Fairen, Mónica; Nuñez Llaves, Raul; Olivé Roig, Claudia; García-Ribas, Guillermo; Menéndez-González, Manuel; Martínez, Carmen; Aguilar, Miquel; Buongiorno, Mariateresa; Franco-Macías, Emilio; Saez, Maria Eugenia; Cano, Amanda; Bullido Gómez-Heras, Maria Jesús; Real-Navarrete, Luis Miguel; Rodríguez-Rodríguez, Eloy; Royo-Sánchez-Palencia, José Luis; Álvarez, Victoria; Pastor, Pau; Piñol-Ripoll, Gerard; Mir, Pablo; Calero Lara, Miguel; Medina Padilla, Miguel; Sánchez-Juan, Pascual; Carracedo Álvarez, Ángel María; Valero, Sergi; Hernández, Isabel; Tàrraga, Lluis; Ramirez, Alfredo; Boada, Mercé; Ruiz Laza, Agustín[et al.] (IOAP-MDPI, 2023-01-04)Mosaic loss of chromosome Y (mLOY) is a common ageing-related somatic event and has been previously associated with Alzheimer’s disease (AD). However, mLOY estimation from genotype microarray data only reflects the mLOY ...