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Listar por autor "Queipo Ortuño, María Isabel"
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Adipose tissue gene expression of factors related to lipid processing in obesity
Clemente-Postigo, María Mercedes; Queipo Ortuño, María Isabel; Fernandez-García, Diego; Gómez-Huelgas, Ricardo; Tinahones, Francisco J; Cardona, Fernando[et al.] (PLOS One, 2011)Background Adipose tissue lipid storage and processing capacity can be a key factor for obesity-related metabolic disorders such as insulin resistance and diabetes. Lipid uptake is the first step to adipose tissue lipid ... -
Análisis de la relación entre microbiota intestinal, permeabilidad intestinal y niveles de glucemia, en niños con Diabetes Mellitus tipo 1 comparados con niños con diabetes tipo MODY 2 y controles sanos
Martín Tejedor, Beatriz María (UMA Editorial, 2017)La Diabetes Mellitus tipo 1 (DM1) es una enfermedad inmunomediada de origen multifactorial que está sufriendo un aumento de incidencia en las últimas décadas. Esta enfermedad presenta una elevada morbilidad, precisando un ... -
Beneficial Effects of Essential Oils from the Mediterranean Diet on Gut Microbiota and Their Metabolites in Ischemic Heart Disease and Type-2 Diabetes Mellitus
Sánchez-Quintero, María José; Delgado, Josué; Medina-Vera, Dina; Becerra-Muñoz, Víctor Manuel; Queipo-Ortuño, María Isabel; Estévez, Mario; Plaza-Andrades, Isaac; Rodríguez Capitán, Jorge; Sánchez, Pedro L.; Crespo-Leiro, María G.; Jiménez-Navarro, Manuel Francisco; Pavón-Morón, Francisco Javier[et al.] (IOAP-MPDI, 2022-11-03)Ischemic heart disease (IHD) and type-2 diabetes mellitus (T2DM) remain major health problems worldwide and commonly coexist in individuals. Gut microbial metabolites, such as trimethylamine N-oxide (TMAO) and short-chain ... -
Caracterización de microbiota fecal en pacientes con Diabetes Mellitus tipo 1 y su relación con niveles de glucemia y estrés oxidativo
Leiva Gea, Isabel (Universidad de Málaga, Servicio de Publicaciones y Divulgación Científica, 2014)Estudio de casos y control para realizar caracterización de microbiota fecal en pacientes con Diabetes Mellitus Tipo 1 comparada con sujetos sanos así como su relación con niveles de glucemia y estrés oxidativo con 8 ... -
Correlación entre los perfiles de microbiota intratumoral, miRNAs y marcadores transcriptómicos en pacientes con diferentes subtipos de cáncer de endometrio en presencia y ausencia de metástasis.
Boutriq, Soukaina (UMA Editorial, 2023-03-27)En el presente estudio, analizamos la composición de microbiota endometrial entre 10 controles sanos y 58 pacientes con cáncer de endometrio, así como entre la microbiota intratumoral de pacientes con tumores endometrioides ... -
Development of a Novel NGS Methodology for Ultrasensitive Circulating Tumor DNA Detection as a Tool for Early-Stage Breast Cancer Diagnosis
Jiménez-Rodríguez, Begoña; Alba-Bernal, Alfonso; López-López, Esperanza; Quirós-Ortega, María Elena; Carbajosa, Guillermo; Garrido-Aranda, Alicia; Álvarez-Pérez, Martína; Godoy-Ortiz, Ana; Queipo-Ortuño, María Isabel; Vicioso-Recio, Luis Prudencio; Díaz-Córdoba, Gema; Roldán-Díaz, María Dunia; Velasco-Suelto, Jesús; Hernando Melia, Cristina; Bermejo, Begoña; Julve-Parreño, Ana; Lluch, Ana; Pascual, Javier; Comino-Méndez, Iñaki; Alba-Conejo, Emilio[et al.] (IOAP-MDPI, 2022-12-21)Breast cancer (BC) is the most prevalent cancer in women. While usually detected when localized, invasive procedures are still required for diagnosis. Herein, we developed a novel ultrasensitive pipeline to detect circulating ... -
Effect of apolipoprotein C3 and apolipoprotein A1 polymorphisms on postprandial response to a fat overload in metabolic syndrome patients
Clemente-Postigo, María Mercedes; Queipo-Ortuño, María Isabel; Valdivieso-Felices, Pedro; Tinahones-Madueño, Francisco José; Cardona-Díaz, Fernando (Elsevier. The Canadian Society of Clinical Chemists., 2010)Objectives: Apolipoprotein C-III (APOC3) is a component of triglyceride rich lipoproteins, and SstI polymorphism has been associated with hypertriglyceridemia. Apolipoprotein A-I (APOA1) is the major component of HDL and ... -
Endotoxin increase after fat overload is related to postprandial hypertriglyceridemia in morbidly obese patients
Clemente-Postigo, María Mercedes; Queipo-Ortuño, María Isabel; Murri, Mora; Boto-Ordóñez, María; Pérez-Martínez, Pablo; Andrés-Lacueva, Cristina; Cardona-Díaz, Fernando; Tinahones-Madueño, Francisco José[et al.] (American Society for Biochemistry and Molecular Biology, 2012)The low-grade inflammation observed in obesity has been associated with a high-fat diet, though this relation is not fully understood. Bacterial endotoxin, produced by gut microbiota, may be the linking factor. However, ... -
Epigenetics of Adipose Tissue and its related disorders
Castellano Castillo, Daniel (UMA Editorial, 2019-12-20)Obesity and metabolic syndrome are increasing epidemic worldwide, especially in developed countries. Obesity and metabolic disease increase the risk of suffering certain diseases such as diabetes, cardiovascular disease, ... -
FABP4 Dynamics in Obesity: Discrepancies in Adipose Tissue and Liver Expression Regarding Circulating Plasma Levels
Queipo-Ortuño, María Isabel; Escoté Miró, Xavier; Ceperuelo-Mallafré, Victoria; Garrido-Sánchez, Lourdes; Miranda, Merce; Clemente-Postigo, María Mercedes; Pérez-Pérez, Rafael; Peral Fuentes, Belén; Cardona-Díaz, Fernando; Fernández Real, José M; Tinahones-Madueño, Francisco José; Vendrell Ortega, Joan[et al.] (PLOS (Public Library of Science), 2012)Background FABP4 is predominantly expressed in adipose tissue, and its circulating levels are linked with obesity and a poor atherogenic profile. Objective In patients with a wide BMI range, we analyze FABP4 expression ... -
Influence of the microbiome on radiotherapy-induced oral mucositis and its management: A comprehensive review
Fernández Forné, África; García Anaya, María Jesús; Segado Guillot, Salvador José; Plaza-Andrades, Isaac; De-la-Peña-Fernández, Lourdes; Lorca Ocón, María Jesús; Lupiáñez Pérez, Yolanda; Queipo-Ortuño, María Isabel; Gómez-Millán Barrachina, Jaime[et al.] (Elsevier, 2023-07)Radiation-induced mucositis is the most common, debilitating and painful acute toxicity associated with active treatment in head and neck cancer area, severely affecting more than 65% of patients. Oral microbiota significantly ... -
Multi-Omics Approach Reveals Prebiotic and Potential Antioxidant Effects of Essential Oils from the Mediterranean Diet on Cardiometabolic Disorder Using Humanized Gnotobiotic Mice.
Sánchez-Quintero, María José; Delgado, Josué; Martín-Chaves, Laura; Medina-Vera, Dina; Murri, Mora; Becerra-Muñoz, Víctor Manuel; Estévez, Mario; Crespo-Leiro, María G.; Paz López, Guillermo; González-Jiménez, Andrés; García-Ranea, Juan Antonio; Queipo-Ortuño, María Isabel; Plaza-Andrades, Isaac; Rodríguez Capitán, Jorge; Pavón-Morón, Francisco Javier; Jiménez-Navarro, Manuel Francisco[et al.] (MDPI, 2023-08-20)Essential oils sourced from herbs commonly used in the Mediterranean diet have demonstrated advantageous attributes as nutraceuticals and prebiotics within a model of severe cardiometabolic disorder. The primary objective ... -
Nuevos biomarcadores en cáncer de mama: microARNs, microbiota y vía melatonérgica.
Laborda-Illanes, Aurora (UMA Editorial, 2024)El cáncer de mama (CM) es una importante causa de morbilidad y mortalidad relacionada con el cáncer a nivel mundial, principalmente debido a la metástasis. Los subtipos más comunes son aquellos que poseen receptores ... -
RNA expression changes driven by altered epigenetics status related to NASH etiology
Castellano Castillo, Daniel; Ramos-Molina, Bruno; Frutos, María Dolores; Arranz-Salas, Isabel María; Reyes-Engel, Armando; Queipo-Ortuño, María Isabel; Cardona-Díaz, Fernando[et al.] (ELSEVIER, 2024-04)Non-alcoholic fatty liver disease (NAFLD) is a growing health problem due to the increased obesity rates, among other factors. In its more severe stage (NASH), inflammation, hepatocellular ballooning and fibrosis are ... -
Role of intestinal microbiota composition in colorectal cancer and in the response to neoadjuvant radiochemotherapy previous to surgery
Sanchez Alcoholado, Lidia (UMA Editorial, 2022-01-25)Intestinal-microbiota has been associated with different diseases, among which are obesity and colorectal cancer (CRC), microbiota is assumed to be a possible link between both disorders. Due to this, the composition of ... -
Synergic effect of metabolic syndrome and lipodystrophy on oxidative stress and inflammation process in treated HIV-patients.
González-Doménech, Carmen María; Plaza-Andrades, Isaac; Garrido-Sánchez, Lourdes; Queipo-Ortuño, María Isabel (Elsevier, 2022-06-06)The aim of this study was to assess the effect of lipodystrophy (LD) associated to metabolic syndrome (MS) on oxidative stress and inflammation in a cohort of 243 HIV-infected patients with MS, all of them under three ...