Listar por autor "Queipo-Ortuño, María Isabel"
Mostrando ítems 1-19 de 19
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Análisis de la relación entre microbiota intestinal, permeabilidad intestinal y niveles de glucemia, en niños con Diabetes Mellitus tipo 1 comparados con niños con diabetes tipo MODY 2 y controles sanos
(UMA Editorial, 2017)La Diabetes Mellitus tipo 1 (DM1) es una enfermedad inmunomediada de origen multifactorial que está sufriendo un aumento de incidencia en las últimas décadas. Esta enfermedad presenta una elevada morbilidad, precisando un ... -
Association between metabolic status and the methylation level of genes involved in metabolic disorders and obesity
Castellano-Castillo, Daniel; Moreno-Indias, Isabel; Picon-Cesar, María José; Garcia-Aleman, Jorge; Macias-Gonzalez, Manuel; Tinahones-Madueño, Francisco José
; Queipo-Ortuño, María Isabel; Cardona-Díaz, Fernando[et al.] (2014-08-01)
Objectives: DNA methylation is one of the epigenetic mechanims to control gene expression, and it is believed to be modulated by environmental and nutritional factors. Thus, epigenetics provides a mechanism which may explain ... -
Beneficial Effects of Essential Oils from the Mediterranean Diet on Gut Microbiota and Their Metabolites in Ischemic Heart Disease and Type-2 Diabetes Mellitus
Sánchez-Quintero, María José; Delgado, Josué; Medina-Vera, Dina; Becerra-Muñoz, Víctor Manuel; Queipo-Ortuño, María Isabel; Estévez, Mario; Plaza-Andrades, Isaac; Rodríguez Capitán, Jorge; Sánchez, Pedro L.; Crespo-Leiro, María G.; Jiménez-Navarro, Manuel Francisco; Pavón-Morón, Francisco Javier[et al.] (IOAP-MPDI, 2022-11-03)
Ischemic heart disease (IHD) and type-2 diabetes mellitus (T2DM) remain major health problems worldwide and commonly coexist in individuals. Gut microbial metabolites, such as trimethylamine N-oxide (TMAO) and short-chain ... -
Caracterización de microbiota fecal en pacientes con Diabetes Mellitus tipo 1 y su relación con niveles de glucemia y estrés oxidativo
(Universidad de Málaga, Servicio de Publicaciones y Divulgación Científica, 2014)Estudio de casos y control para realizar caracterización de microbiota fecal en pacientes con Diabetes Mellitus Tipo 1 comparada con sujetos sanos así como su relación con niveles de glucemia y estrés oxidativo con 8 ... -
Correlación entre los perfiles de microbiota intratumoral, miRNAs y marcadores transcriptómicos en pacientes con diferentes subtipos de cáncer de endometrio en presencia y ausencia de metástasis.
(UMA Editorial, 2023-03-27)En el presente estudio, analizamos la composición de microbiota endometrial entre 10 controles sanos y 58 pacientes con cáncer de endometrio, así como entre la microbiota intratumoral de pacientes con tumores endometrioides ... -
Development of a Novel NGS Methodology for Ultrasensitive Circulating Tumor DNA Detection as a Tool for Early-Stage Breast Cancer Diagnosis
Jiménez-Rodríguez, Begoña; Alba-Bernal, Alfonso; López-López, Esperanza; Quirós-Ortega, María Elena; Carbajosa, Guillermo; Garrido-Aranda, Alicia; Álvarez-Pérez, Martína; Godoy-Ortiz, Ana; Queipo-Ortuño, María Isabel; Vicioso-Recio, Luis Prudencio; Díaz-Córdoba, Gema; Roldán-Díaz, María Dunia; Velasco-Suelto, Jesús; Hernando Melia, Cristina; Bermejo, Begoña; Julve-Parreño, Ana; Lluch, Ana; Pascual, Javier; Comino-Méndez, Iñaki; Alba-Conejo, Emilio[et al.] (IOAP-MDPI, 2022-12-21)
Breast cancer (BC) is the most prevalent cancer in women. While usually detected when localized, invasive procedures are still required for diagnosis. Herein, we developed a novel ultrasensitive pipeline to detect circulating ... -
Effect of acute and chronic red wine consumption on lipopolysaccharide concentrations
Clemente-Postigo, María Mercedes; Queipo-Ortuño, María Isabel; Boto-Ordóñez, María; Coín-Aragüez, Leticia I.; Roca-Rodríguez, María del Mar; Delgado-Lista, J.; Cardona-Díaz, Fernando; Andrés-Lacueva, Cristina; Tinahones-Madueño, Francisco José[et al.] (Elsevier (The American Journal of Clinical Nutrition), 2013)
Background: Chronic red wine (RW) consumption has been associated with decreased cardiovascular disease risk, mainly attributed to an improvement in lipid profile. RW intake is also able to change the composition of gut ... -
Effect of apolipoprotein C3 and apolipoprotein A1 polymorphisms on postprandial response to a fat overload in metabolic syndrome patients
Clemente-Postigo, María Mercedes; Queipo-Ortuño, María Isabel; Valdivieso-Felices, Pedro; Tinahones-Madueño, Francisco José; Cardona-Díaz, Fernando (Elsevier. The Canadian Society of Clinical Chemists., 2010)
Objectives: Apolipoprotein C-III (APOC3) is a component of triglyceride rich lipoproteins, and SstI polymorphism has been associated with hypertriglyceridemia. Apolipoprotein A-I (APOA1) is the major component of HDL and ... -
Endotoxin increase after fat overload is related to postprandial hypertriglyceridemia in morbidly obese patients
Clemente-Postigo, María Mercedes; Queipo-Ortuño, María Isabel; Murri, Mora; Boto-Ordóñez, María; Pérez-Martínez, Pablo; Andrés-Lacueva, Cristina; Cardona-Díaz, Fernando; Tinahones-Madueño, Francisco José[et al.] (American Society for Biochemistry and Molecular Biology, 2012)
The low-grade inflammation observed in obesity has been associated with a high-fat diet, though this relation is not fully understood. Bacterial endotoxin, produced by gut microbiota, may be the linking factor. However, ... -
Epigenetics of Adipose Tissue and its related disorders
(UMA Editorial, 2019-12-20)Obesity and metabolic syndrome are increasing epidemic worldwide, especially in developed countries. Obesity and metabolic disease increase the risk of suffering certain diseases such as diabetes, cardiovascular disease, ... -
FABP4 Dynamics in Obesity: Discrepancies in Adipose Tissue and Liver Expression Regarding Circulating Plasma Levels
Queipo-Ortuño, María Isabel; Escoté Miró, Xavier; Ceperuelo-Mallafré, Victoria; Garrido-Sánchez, Lourdes; Miranda, Merce; Clemente-Postigo, María Mercedes; Pérez-Pérez, Rafael; Peral Fuentes, Belén; Cardona-Díaz, Fernando; Fernández Real, José M; Tinahones-Madueño, Francisco José; Vendrell Ortega, Joan[et al.] (PLOS (Public Library of Science), 2012)
Background FABP4 is predominantly expressed in adipose tissue, and its circulating levels are linked with obesity and a poor atherogenic profile. Objective In patients with a wide BMI range, we analyze FABP4 expression ... -
Influence of red wine polyphenols and ethanol on the gut microbiota ecology and biochemical biomarkers
Queipo-Ortuño, María Isabel; Boto-Ordóñez, María; Murri Pierri, Mora; Gómez-Zumaquero, Juan Miguel; Clemente-Postigo, María Mercedes; Estruch, Ramón; Cardona-Díaz, Fernando; Andrés-Lacueva, Cristina; Tinahones-Madueño, Francisco José[et al.] (Elsevier (American Society for Nutrition), 2012)
Background: Few studies have investigated the effect of dietary polyphenols on the complex human gut microbiota, and they focused mainly on single polyphenol molecules and select bacterial populations. Objective: The ... -
Influence of the microbiome on radiotherapy-induced oral mucositis and its management: A comprehensive review
Fernández Forné, África; García Anaya, María Jesús; Segado Guillot, Salvador José; Plaza-Andrades, Isaac; De-la-Peña-Fernández, Lourdes; Lorca Ocón, María Jesús; Lupiáñez Pérez, Yolanda; Queipo-Ortuño, María Isabel; Gómez-Millán Barrachina, Jaime[et al.] (Elsevier, 2023-07)
Radiation-induced mucositis is the most common, debilitating and painful acute toxicity associated with active treatment in head and neck cancer area, severely affecting more than 65% of patients. Oral microbiota significantly ... -
Multi-Omics Approach Reveals Prebiotic and Potential Antioxidant Effects of Essential Oils from the Mediterranean Diet on Cardiometabolic Disorder Using Humanized Gnotobiotic Mice.
Sánchez-Quintero, María José; Delgado, Josué; Martín-Chaves, Laura; Medina-Vera, Dina; Murri, Mora; Becerra-Muñoz, Víctor Manuel; Estévez, Mario; Crespo-Leiro, María G.; Paz López, Guillermo; González-Jiménez, Andrés; García-Ranea, Juan Antonio; Queipo-Ortuño, María Isabel; Plaza-Andrades, Isaac; Rodríguez Capitán, Jorge; Pavón-Morón, Francisco Javier; Jiménez-Navarro, Manuel Francisco[et al.] (MDPI, 2023-08-20)
Essential oils sourced from herbs commonly used in the Mediterranean diet have demonstrated advantageous attributes as nutraceuticals and prebiotics within a model of severe cardiometabolic disorder. The primary objective ... -
Nuevos biomarcadores en cáncer de mama: microARNs, microbiota y vía melatonérgica.
(UMA Editorial, 2024)El cáncer de mama (CM) es una importante causa de morbilidad y mortalidad relacionada con el cáncer a nivel mundial, principalmente debido a la metástasis. Los subtipos más comunes son aquellos que poseen receptores ... -
Quantitative real-time polymerase chain reaction improves conventional microbiological diagnosis in an outbreak of brucellosis due to ingestion of unpasteurized goat cheese.
Colmenero Castillo, Juan de Dios; Clavijo-Frutos, Encarnación; Morata-Losa, María Pilar; Bravo-Romero, María José; Queipo-Ortuño, María Isabel (Elsevier, 2011-11)
Rapid diagnosis of individuals involved in brucellosis outbreaks can sometimes be difficult with conventional microbiological techniques. We analyzed, for the first time, the diagnostic yield of a real-time polymerase chain ... -
RNA expression changes driven by altered epigenetics status related to NASH etiology
Castellano Castillo, Daniel; Ramos-Molina, Bruno; Frutos, María Dolores; Arranz-Salas, Isabel María; Reyes-Engel, Armando; Queipo-Ortuño, María Isabel; Cardona-Díaz, Fernando[et al.] (ELSEVIER, 2024-04)
Non-alcoholic fatty liver disease (NAFLD) is a growing health problem due to the increased obesity rates, among other factors. In its more severe stage (NASH), inflammation, hepatocellular ballooning and fibrosis are ... -
Role of intestinal microbiota composition in colorectal cancer and in the response to neoadjuvant radiochemotherapy previous to surgery
(UMA Editorial, 2022-01-25)Intestinal-microbiota has been associated with different diseases, among which are obesity and colorectal cancer (CRC), microbiota is assumed to be a possible link between both disorders. Due to this, the composition of ... -
Synergic effect of metabolic syndrome and lipodystrophy on oxidative stress and inflammation process in treated HIV-patients.
González-Doménech, Carmen María; Plaza-Andrades, Isaac; Garrido-Sánchez, Lourdes; Queipo-Ortuño, María Isabel (Elsevier, 2022-06-06)
The aim of this study was to assess the effect of lipodystrophy (LD) associated to metabolic syndrome (MS) on oxidative stress and inflammation in a cohort of 243 HIV-infected patients with MS, all of them under three ...