Listar por autor "Arranz-Salas, Isabel"
Mostrando ítems 1-12 de 12
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8-oxoguanine DNA glycosylase 1 upregulation as a risk factor for obesity and colorectal cancer
Pilo, Jesús; García-Flores, Libia Alejandra; Clemente-Postigo, María Mercedes
; Arranz-Salas, Isabel María; Alcaide, Julia; Ramos-Fernandez, Maria; Lozano-Castro, José; Boughanem Lakhal, Hatim; Kompella, Pallavi; Macías-González, Manuel[et al.] (MDPI, 2023-03-13)
DNA damage has been extensively studied as a potentially helpful tool in assessing and preventing cancer, having been widely associated with the deregulation of DNA damage repair (DDR) genes and with an increased risk of ... -
Differential iNKT and T cells activation in non-alcoholic fatty liver disease and drug-induced liver injury.
Caballano-Infantes, Estefanía; García-García, Alberto; Lopez-Gomez, Carlos; Cueto-Sánchez, Alejandro; Robles-Díaz, María Mercedes; Ortega-Alonso, Aida; Martín-Reyes, Flores; Alvarez-Alvarez, Ismael; Arranz-Salas, Isabel María; Ruiz-Cabello, Francisco; Lucena-González, María Isabel; García-Fuentes, Eduardo; Andrade-Bellido, Raúl Jesús; García-Cortés, Miren[et al.] (MDPI, 2021-01-28)
Background: Non-alcoholic fatty liver disease (NAFLD) and idiosyncratic drug-induced liver injury (DILI) could share molecular mechanisms involving the immune system. We aimed to identify activation immunological biomarkers ... -
Estudio de factores predictivos de respuesta patológica a quimioterapia neoadyuvante en el cáncer de mama receptores hormonales positivos HER2 negativo
Lavado-Fernández, Ana Isabel; Álvarez-Pérez, Martína; Prieto Cuadra, Juan Daniel; Jiménez-Rodríguez, Begoña; Lozano, María José; De Luque, Vanessa; Jiménez-Vista, Álvaro; Ventura, Carmen; Jiménez-Fernández, Ana; Rodrigo, Isabel; Ramírez, César; Cano, Tatiana; González-Zafra, Virginia; Pérez-Villa, Lidia; Gallego-Domínguez, Elena María; Ortega-Jiménez, María Victoria; Arranz-Salas, Isabel María; Ribelles, Nuria; Alba-Conejo, Emilio; Vicioso-Recio, Luis Prudencio[et al.] (2015-07-02)
La quimioterapia neoadyuvante (QTN) se utiliza cada vez más para conseguir una reducción tumoral que permita una cirugía conservadora y, mediante el grado de respuesta patológica tumoral, determinar el pronóstico de las ... -
Gastric microbiota-specific signatures in adults with obesity and Helicobacter pylori-negative gastritis
Martínez-Montoro, José Ignacio; Sancho-Marín, Raquel; Ocaña-Wilhelmi, Luis Tomás; Arranz-Salas, Isabel; Ruiz-Campos, Nerea; García-López, María José; Tinahones-Madueño, Francisco José; Gutiérrez-Repiso, Carolina[et al.] (Wiley, 2025-06-07)
Background The role of the gastric microbiome in the pathophysiology of gastritis beyond Helicobacter pylori (HP) infection is poorly understood and has remained unexplored in patients with obesity. The aim of this study ... -
Gastrointestinal cancer: Relationship between histology and microbiota
García Sanz, A; Escamilla-Sánchez, Alejandro; Mercado-Sáenz, Silvia; Rodríguez-Pérez, Luis Manuel; Arranz-Salas, Isabel María; Sánchez-Varo, Raquel María; Peláez-González, Alberto Carlos; López-Villodres, Juan Antonio; Bermúdez-Flores, Diego Teófilo[et al.] (2022-09-09)
Objectives: Review of the published literature concerning the relationship between microbiome and gastrointestinal cancer. Methods: Present work is focused on systematic research in the most prominent biomedical databases ... -
Gastrointestinal Stromal Tumor (GIST) and its relationship with germline mutations
Arranz-Salas, Isabel María; Jiménez-Campillo, Marta; Hierro-Martín, María Isabel; Ortega-Jiménez, María Victoria; Mercado-Sáenz, Silvia; Rodríguez-Pérez, Luis Manuel; Sánchez-Varo, Raquel María; Escamilla-Sánchez, Alejandro; Peláez-González, Alberto Carlos; Bermúdez-Flores, Diego Teófilo[et al.] (2022)
We present the case of a 38-year-old man with a history of abdominal paraganglioma 10 years ago, who consulted for hematemesis and asthenia of 5 days' evolution. An upper gastrointestinal endoscopy was performed where a ... -
Her2-Positive and Microsatellite Instability Status in Gastric Cancer—Clinicopathological Implications
Bermúdez, Ana; Arranz-Salas, Isabel María; Mercado-Sáenz, Silvia; López-Villodres, Juan Antonio; González, Virginia; Ríus-Díaz, Francisca; Ortega-Jiménez, María Victoria; Alba-Linero, Carmen; Hierro-Martín, María Isabel; Bermúdez-Flores, Diego Teófilo[et al.] (MDPI, 2021-03-21)
Gastric cancer (GC) is one of the leading causes of cancer-related death. The combination of new molecular classifications with clinicopathological data could contribute to the individualization of patients and to the ... -
Microbiome alterations and Alzheimer's Disease: modeling strategies with transgenic mice.
López-Villodres, Juan Antonio; Escamilla-Sánchez, Alejandro; Mercado-Sáenz, Silvia; Alba-Tercedor, Carmen; Rodríguez-Pérez, Luis Manuel; Arranz-Salas, Isabel María; Sánchez-Varo, Raquel María; Bermúdez-Flores, Diego Teófilo[et al.] (MDPI, 2023-06-27)
In the last decade, the role of the microbiota-gut-brain axis has been gaining momentum in the context of many neurodegenerative and metabolic disorders, including Alzheimer's disease (AD) and diabetes, respectively. ... -
Non‑alcoholic fatty liver disease in patients with morbid obesity: the gut microbiota axis as a potential pathophysiology mechanism
Cornejo Pareja, Isabel María; Mohamed-Reda, Amiar; Ocaña-Wilhelmi, Luis Tomás; Soler Humanes, Rocio; Arranz-Salas, Isabel María; Garrido-Sánchez, Lourdes; Gutiérrez-Repiso, Carolina; Tinahones-Madueño, Francisco José[et al.] (Springer Nature, 2024-01-24)
Alterations in gut microbiota are associated with the pathogenesis of metabolic diseases, including metabolic-associated fatty liver disease (MAFLD). The aim of this study was to evaluate gut microbiota composition and ... -
Oligodendrocyte metabolism throughout its differentiation: immunocytochemistry study and its impact in remyelination
Gismero Rodríguez, Javier; López-Villodres, Juan Antonio; Escamilla-Sánchez, Alejandro; García Díaz, Beatriz; Rodríguez-Pérez, Luis Manuel; Mercado-Sáenz, Silvia; Ortega-Jiménez, María Victoria; Arranz-Salas, Isabel María; Peláez-González, Alberto Carlos; Bermúdez-Flores, Diego Teófilo[et al.] (2022-09-07)
Introduction: Oligodendrocytes (OL) role in demyelinating pathologies such as multiple sclerosis and other neurodegenerative diseases is only recently being subject of extensive research. While the genetic and molecular ... -
Protein homeostasis as a therapeutical target for Alzheimer’s disease: analysis in the hippocampus of transgenic mouse models
Sánchez-Varo, Raquel María; Criado-Álamo, Elena; Fernández-Valenzuela, Juan José; Mercado-Sáenz, Silvia; López-Villodres, Juan Antonio; Escamilla-Sánchez, Alejandro; Rodríguez-Pérez, Luis Manuel; Arranz-Salas, Isabel María; Ortega-Jiménez, Concepción; Alba-Tercedor, Carmen; Gutiérrez-Pérez, Antonia[et al.] (2022-09)
Alzheimer's disease (AD) constitutes the most prevalent form of dementia. There is no cure so there is an urgent need of novel therapeutic targets and treatments. The main histopathological hallmarks of AD brains are ... -
RNA expression changes driven by altered epigenetics status related to NASH etiology
Castellano Castillo, Daniel; Ramos-Molina, Bruno; Frutos, María Dolores; Arranz-Salas, Isabel María; Reyes-Engel, Armando; Queipo-Ortuño, María Isabel; Cardona-Díaz, Fernando[et al.] (ELSEVIER, 2024-04)
Non-alcoholic fatty liver disease (NAFLD) is a growing health problem due to the increased obesity rates, among other factors. In its more severe stage (NASH), inflammation, hepatocellular ballooning and fibrosis are ...