Listar por autor "Tinahones-Madueño, Francisco José"
Mostrando ítems 1-20 de 59
-
Adipogenic Impairment of Adipose Tissue-Derived Mesenchymal Stem Cells in Subjects With Metabolic Syndrome: Possible Protective Role of FGF2
Oliva Olivera, Wilfredo; Coín-Aragüez, Leticia I.; Lhamyani, Said; Clemente-Postigo, María Mercedes
; Alcaide Torres, Juan; Bernal-López, María Rosa; El-Bekay, Rajaa; Tinahones-Madueño, Francisco José[et al.] (Endocrine Society, 2017)
Context: The decreased expansion capacity of adipose tissue plays a crucial role in the onset of disorders associated with metabolic syndrome. Objetive: The aim of this study was to examine the state of adipose tissue-derived ... -
Adipose tissue inflammation and VDR expression and methylation in colorectal cancer
Castellano-Castillo, Daniel; Morcillo Espina, Sonsoles; Clemente-Postigo, María Mercedes; Crujeiras Martínez, Ana Belén; Fernández-García, José Carlos; Torres Sánchez, Esperanza; Tinahones-Madueño, Francisco José; Macías-González, Manuel[et al.] (BMC (Part of Springer Nature), 2018)
Background: Lack of vitamin D (VD) has been associated with colorectal cancer (CRC). VD has anti-inflammatory effects and regulates several cellular pathways by means of its receptor, including epigenetic modifications. ... -
Association between metabolic status and the methylation level of genes involved in metabolic disorders and obesity
Castellano-Castillo, Daniel; Moreno-Indias, Isabel; Picon-Cesar, María José; Garcia-Aleman, Jorge; Macias-Gonzalez, Manuel; Tinahones-Madueño, Francisco José; Queipo-Ortuño, María Isabel; Cardona-Díaz, Fernando[et al.] (2014-08-01)
Objectives: DNA methylation is one of the epigenetic mechanims to control gene expression, and it is believed to be modulated by environmental and nutritional factors. Thus, epigenetics provides a mechanism which may explain ... -
Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer
Boughanem, Hatim; Cabrera-Mulero, Amanda; Hernández Alonso, Daniel; Clemente-Postigo, María Mercedes; Casanueva, Felipe F.; Tinahones-Madueño, Francisco José; Morcillo Espina, Sonsoles; Crujeiras Martínez, Ana Belén; Macías-González, Manuel[et al.] (Springer Nature, 2020)
Colorectal cancer (CRC) results from the accumulation of epigenetic and genetic changes in colon cells during neoplasic transformation, which the activation of Wingless (Wnt) signaling pathway is a common mechanism for CRC ... -
Biomarcadores en tejido adiposo asociados a la temprana resolución de diabetes tipo 2 en pacientes sometidos a cirugía bariátrica
(Servicio de Publicaciones y Divulgación Científica, 2015)La obesidad se considera uno de los problemas más relevantes en salud pública. Existe una alta prevalencia de obesidad y sobrepeso en los pacientes con diabetes tipo 2 (DM). La cirugía bariátrica ha demostrado ser el ... -
Cambios en la microbiota intestinal en pacientes con diabetes tipo 2 e intolerancia a metformina tras la reintroducción de la misma.
(UMA Editorial, 2023)Introducción: Metformina es el tratamiento de primera línea en diabetes mellitus tipo 2 (DM2), aunque la presencia de efectos adversos gastrointestinales favorece su discontinuación. La etiopatogenia de la intolerancia ... -
Cambios en las hormonas reguladoras de la ingesta, microbiota intestinal y metabolismo hidrocarbonado, antes y después del tratamiento antibiótico erradicador en pacientes con Helicobacter pylori positivo.
(UMA Editorial, 2017-06-12)Introducción. La creciente prevalencia de las enfermedades metabólicas conlleva una investigación continua de su etiopatogenia. Existen trabajos controvertidos sobre la infección por H. pylori y sus posibles efectos ... -
Differences in the neovascular potential of thymus versus subcutaneous adipose-derived stem cells from patients with myocardial ischaemia.
Oliva Olivera, Wilfredo; Coín-Aragüez, Leticia I.; Lhamyani, Said; Salas-Millán, Manuel Julián; Gentile, Adriana Mariel; Romero-Zerbo, Silvana Yanina; Zayed, Hatem; Valderrama-Marcos, José Francisco; Tinahones-Madueño, Francisco José; El-Bekay, Rajaa[et al.] (Wiley, 2017)
Adipose tissue‐derived multipotent mesenchymal cells (ASCs) participate in the information ofblood vessels under hypoxic conditions. It is probable that the susceptibility of ASCs to theinfluence of age and ageing‐associated ... -
Efectos del consumo moderado de bebidas fermentadas con distinto contenido de polifenoles en la microbiota intestinal.
(UMA Editorial, 2024)El consumo moderado de bebidas fermentadas, como el vino tinto, se ha asociado con efectos beneficiosos cardiovasculares y metabólicos. De manera similar, otras bebidas fermentadas, como la cerveza, podrían tener efectos ... -
Effect of acute and chronic red wine consumption on lipopolysaccharide concentrations
Clemente-Postigo, María Mercedes; Queipo-Ortuño, María Isabel; Boto-Ordóñez, María; Coín-Aragüez, Leticia I.; Roca-Rodríguez, María del Mar; Delgado-Lista, J.; Cardona-Díaz, Fernando; Andrés-Lacueva, Cristina; Tinahones-Madueño, Francisco José[et al.] (Elsevier (The American Journal of Clinical Nutrition), 2013)
Background: Chronic red wine (RW) consumption has been associated with decreased cardiovascular disease risk, mainly attributed to an improvement in lipid profile. RW intake is also able to change the composition of gut ... -
Effect of an intensive lifestyle intervention on cystatin C–based kidney function in adults with overweight and obesity: From the PREDIMED-Plus trial
Martínez-Montoro, José Ignacio; Cornejo Pareja, Isabel María; Díaz-López, Andrés; Sureda, Antoni; Toledo, Estefanía; Babio, Nancy; Tur, Josep A.; Martínez-González, Miguel A.; Martínez, J. Alfredo; Fito, Montse; Salas-Salvadó, Jordi; Tinahones-Madueño, Francisco José; PREDIMED-Plus Investigators[et al.] (Wiley, 2024)
In older adults with overweight/obesity and metabolic syndrome, the PREDIMED-Plus intervention may be an optimal approach to pre-serve kidney function. -
Effect of apolipoprotein C3 and apolipoprotein A1 polymorphisms on postprandial response to a fat overload in metabolic syndrome patients
Clemente-Postigo, María Mercedes; Queipo-Ortuño, María Isabel; Valdivieso-Felices, Pedro; Tinahones-Madueño, Francisco José; Cardona-Díaz, Fernando (Elsevier. The Canadian Society of Clinical Chemists., 2010)
Objectives: Apolipoprotein C-III (APOC3) is a component of triglyceride rich lipoproteins, and SstI polymorphism has been associated with hypertriglyceridemia. Apolipoprotein A-I (APOA1) is the major component of HDL and ... -
Effect of Moderate Consumption of Different Phenolic-Content Beers on the Human Gut Microbiota Composition: A Randomized Crossover Trial
Martínez-Montoro, José Ignacio; Quesada-Molina, Mar; Gutiérrez-Repiso, Carolina; Ruiz-Limón, Patricia; Subiri-Verdugo, Alba; Tinahones-Madueño, Francisco José; Moreno-Indias, Isabel[et al.] (IOAP-MPDI, 2022-03-21)
The moderate consumption of beer has been associated with positive effects on health, and these benefits are driven, in part, by the antioxidant properties of phenolic compounds found in this beverage. However, the potential ... -
Effects of exercise timing on metabolic health
Martínez-Montoro, José Ignacio; Benítez-Porres, Javier; Tinahones-Madueño, Francisco José; Ortega-Gómez, Almudena; Murri, Mora (Wiley, 2023)
The increasing prevalence of metabolic syndrome is associated with major health and socioeconomic consequences. Currently, physical exercise, together with dietary interventions, is the mainstay of the treatment of obesity ... -
Effects of GLP-1 receptor agonists on neurological complications of diabetes
García-Casares, Natalia; González-González, Guillermo; De-la-Cruz-Cosme, Carlos; Garzón-Maldonado, Francisco Javier; De-Rojas-Leal, Carmen; Ariza-Corbo, María José; Narváez-Peláez, Manuel; Barbancho-Fernández, Miguel Ángel; García-Arnés, Juan Antonio; Tinahones-Madueño, Francisco José[et al.] (Springer, 2023)
Emerging evidence suggests that treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) could be an interesting treatment strategy to reduce neurological complications such as stroke, cognitive impairment, and ... -
Effects of glucagon-like peptide-1 on the differentiation and metabolism of human adipocytes.
El-Bekay, Rajaa; Coín-Aragüez, Leticia I.; Fernandez-García, Diego; Oliva Olivera, Wilfredo; Bernal-López, María Rosa; Clemente-Postigo, María Mercedes; Delgado-Lista, Javier; Díaz-Ruiz, Alberto; Guzmán-Ruiz, Rocio; Vázquez-Martínez, Rafael; Lhamyani, Said; Roca-Rodríguez, María del Mar; Fernández-Veledo, Sonia; Vendrell, Joan; Malagón, Maria M.; Tinahones-Madueño, Francisco José[et al.] (British Pharmacological Society, 2016-03-18)
Glucagon-like peptide-1 (GLP-1) analogues improve glycaemic control in type 2 diabetic (T2D) patients and cause weight loss in obese subjects by as yet unknown mechanisms. We recently demonstrated that the GLP-1 receptor, ... -
Effects of testosterone and metformin on the GlycanAge index of biological age and the composition of the IgG glycome
Vinicki, Martina; Pribić, Tea; Vučković, Frano; Frkatović‑Hodžić, Azra; Plaza-Andrades, Isaac; Tinahones-Madueño, Francisco José; Raffaele, Joseph; Fernández-García, José Carlos; Lauc, Gordan[et al.] (Springer, 2024)
With aging, the body’s ability to maintain regular functions declines, increasing susceptibility to age-related diseases. Therapeutic interventions targeting the underlying biological changes of aging hold promise for ... -
Endotoxin increase after fat overload is related to postprandial hypertriglyceridemia in morbidly obese patients
Clemente-Postigo, María Mercedes; Queipo-Ortuño, María Isabel; Murri, Mora; Boto-Ordóñez, María; Pérez-Martínez, Pablo; Andrés-Lacueva, Cristina; Cardona-Díaz, Fernando; Tinahones-Madueño, Francisco José[et al.] (American Society for Biochemistry and Molecular Biology, 2012)
The low-grade inflammation observed in obesity has been associated with a high-fat diet, though this relation is not fully understood. Bacterial endotoxin, produced by gut microbiota, may be the linking factor. However, ... -
Enfermedad metabólica en el paciente con normopeso
(UMA Editorial, 2017-05-18)En los últimos años ha cobrado gran importancia el estudio de la fisiopatología de la obesidad y la enfermedad metabólica asociada, dado el gran incremento de la prevalencia de ambas. Se ha observado que existen grupos de ... -
Epigenetics of Adipose Tissue and its related disorders
(UMA Editorial, 2019-12-20)Obesity and metabolic syndrome are increasing epidemic worldwide, especially in developed countries. Obesity and metabolic disease increase the risk of suffering certain diseases such as diabetes, cardiovascular disease, ...