Listar por autor "Ruiz-Galdón, Maximiliano"
Mostrando ítems 1-11 de 11
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A Functional Pipeline of Genome-Wide Association Data Leads to Midostaurin as a Repurposed Drug for Alzheimer’s Disease
Esteban-Martos, Alvaro; Brokate-Llanos, Ana María; Real-Navarrete, Luis Miguel
; Melgar-Locatelli, Sonia; De Rojas, Itziar; Castro-Zavala, Adriana; Bravo-Romero, María José; Mañas-Padilla, María del Carmen; García-González, Pablo; Ruiz-Galdón, Maximiliano; Pacheco-Sánchez, Beatriz; Polvillo, Rocío; Rodriguez-de-Fonseca, Fernando; González, Irene; Castilla-Ortega, María Estela; Muñoz-Gómez, Manuel; Rivera, Patricia; Reyes-Engel, Armando; Ruiz, Agustín; Royo-Sánchez-Palencia, José Luis[et al.] (MDPI, 2023)
Genome-wide association studies (GWAS) constitute a powerful tool to identify the different biochemical pathways associated with disease. This knowledge can be used to prioritize drugs targeting these routes, paving the ... -
Análisis genético del dimorfismo secual en el eje de folatos-homocisteína en una población tratada con ácido fólico
(UMA Editorial, 2015)Bajo el término folatos se agrupan los derivados del ácido fólico, una familia de vitaminas con actividad biológica equivalente. Su capacidad de transporte de grupos monocarbonados activos en su estructura les confiere ... -
Differential behavior of serum and red blood cell folate during a treatment with levofolinic acid. Gender differences.
Lendínez Ramírez, Ana María; Reyes Palomares, Arturo Lazaro; Pérez Nevot, Beatriz; Cortés Rodríguez, Miriam; Ruiz-Galdón, Maximiliano; Reyes-Engel, Armando[et al.] (Clinical Laboratory Publications, 2014-01-01)
Background: Folates are essential nutrients that maintain nucleotide synthesis and methylation reactions. Folate levels depend essentially on the diet. In the present work, the changes in the folate-homocysteine (Hcy) ... -
Evaluación del uso de las Cadenas Ligeras Libres Kappa en el laboratorio clínico para el diagnóstico de Esclerosis Múltiple.
(UMA Editorial, 2024)Actualmente en el diagnóstico de la esclerosis múltiple (EM) se incluye como parámetro de laboratorio “gold standard” la presencia de bandas oligoclonales (BOC) de IgG en el líquido cefalorraquídeo (LCR), ausentes en suero. ... -
Genetic Polymorphisms in Folate Pathway Enzymes, DRD4 and GSTM1 Are Related to Temporomandibular Disorder.
Aneiros-Guerrero, Angel; Lendínez-Ramírez, Ana María; Reyes Palomares, Arturo; Pérez-Nevot, Beatriz; Aguado, Lidia; Mayor-Olea, Alvaro; Ruiz-Galdón, Maximiliano; Reyes-Engel, Armando[et al.] (BMC, 2011-05-26)
Methods A case-control study was designed to evaluate the impact of genetic polymorphisms above described on TMD. A total of 229 individuals (69% women) were included at the study; 86 were patients with TMD and 143 were ... -
Genetic polymorphisms of serotonin transporter and receptor 1A could influence success during embryo implantation and maintaining of pregnancy.
Reyes Palomares, Arturo; Lendínez-Ramírez, Ana María; Pérez-Nevot, Beatriz; Cortés-Rodriguez, Miriam; Martínez, Francisco; Garrido, Nicolás; Ruiz-Galdón, Maximiliano; Reyes-Engel, Armando; Reyes-Engel, Armando[et al.] (Elsevier SCI LTD, 2013-02-13)
Objective: To explore whether serotonin-related gene polymorphisms influence clinical outcomes of in vitro fertilization (IVF) treatment in recipients using donated oocytes. Design: Nested case-control study. Setting: ... -
Influence of 5-HTTLPR variants in the SLC6A4 gene over pregnancy outcomes among recipients of donated eggs.
Reyes Palomares, Arturo; Lendínez-Ramírez, Ana María; Pérez-Nevot, Beatriz; Martínez, Francisco; Jiménez, Ana; Ruiz-Galdón, Maximiliano; Reyes-Engel, Armando[et al.] (Oxford University Press, 2011)
Serotonergic activity is regulated by serotonin transporter gene (5-HTT) that is occasionally expressed in migratory cells inside endometrial tissue during early pregnancy decidua. A serotonergic local network has been ... -
Influencia de polimorfismos genéticos asociados al metabolismo de la 5-HT sobre los resultados de FIV/ICSI en receptoras de óvulos donados.
Reyes Palomares, Arturo; Lendínez-Ramírez, Ana María; Martínez Díaz, Francisco; Ruiz-Galdón, Maximiliano; Reyes-Engel, Armando (2012)
NTRODUCCIÓN Y OBJETIVOS La reciente descripción de una red serotoninérgica local en el tracto reproductor femenino, propone el metabolismo de la serotonina (5-HT) como potencial diana terapéutica en medicina reproductiva. ... -
Low Sex Ratio in Children of Professional Basketball Players in Spain
Reyes Palomares, Arturo; Lendínez-Ramírez, Ana María; Ruiz-Galdón, Maximiliano; Reyes-Engel, Armando (Wiley, 2012-05)
The aim of this study was to ascertain the variations in the reproductive sex ratio (number of men to number of women) among male professional basketball players in Spain. This retrospective, cross-sectional study is based ... -
Moderate exercise reveals the influence of ACTN3 R577X and ACE I/D polymorphisms on physical performance in non-athlete active subjects
Alvero-Cruz, José Ramón; Alarcón-Martín, Emilio; García-Romero, Jerónimo; Ruiz-Galdón, Maximiliano; Carrillo-de-Albornoz, Margarita; Polvillo, Rocío; González, Irene; Reyes-Engel, Armando; Royo-Sánchez-Palencia, José Luis[et al.] (Elsevier, 2023)
Genome variations contribute to the vast majority of interindividual differences and may decisively influence sports capability. This study was conceived as a means of finding out when exactly polymorphisms start being ... -
Profiling the Influence of Gene Variants Related to Folate-Mediated One-Carbon Metabolism on the Outcome of In Vitro Fertilization (IVF) with Donor Oocytes in Recipients Receiving Folic Acid Fortification
Reyes Palomares, Arturo Lazaro; Ruiz-Galdón, Maximiliano; Liu, Kui; Reyes-Engel, Armando; Rodriguez-Wallberg, Kenny A. (IOAP-MPDI, 2022-09-25)
Nutritional status and gene polymorphisms of one-carbon metabolism confer a well-known interaction that in pregnant women may affect embryo viability and the health of the newborn. Folate metabolism directly impacts ...