Listar por autor "Baron Van Evercooren, Anne"
Mostrando ítems 1-5 de 5
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Blood vessels guide Schwann cell migration in the adult demyelinated CNS through Eph/ephrin signaling
(Springer Link, 2019)Schwann cells (SC) enter the central nervous system (CNS) in pathophysiological conditions. However, how SC invade the CNS to remyelinate central axons remains undetermined. We studied SC migratory behavior ex vivo and ... -
Generation of oligodendrocytes and establishment of an all-human myelinating platform from human pluripotent stem cells
García-León, Juan Antonio
; Garcia Diaz, Beatriz; Eggermont, Kristel; Cáceres Palomo, Laura; Neyrinck, Katrien; Madeiro da Costa, Rodrigo; Dávila-Cansino, José Carlos; Baron Van Evercooren, Anne; Gutiérrez-Pérez, Antonia; Verfaille, Catherine M[et al.] (Springer Nature, 2020)
Oligodendrocytes (OLs) are responsible for myelin production and metabolic support of neurons. Defects in OLs are crucial in several neurodegenerative diseases including multiple sclerosis (MS) and amyotrophic lateral ... -
Multiple sclerosis iPS-derived oligodendroglia conserve their properties to functionally interact with axons and glia in vivo
(American Association for the Advancement of Science, 2020)Remyelination failure in multiple sclerosis (MS) is associated with a migration/differentiation block of oligodendroglia. The reason for this block is highly debated. It could result from disease-related extrinsic or ... -
Schwann cells: Rescuers of central demyelination
(Wiley, 2020)The presence of peripheral myelinating cells in the central nervous system (CNS) hasgained the neurobiologist attention over the years. Despite the confirmed presence ofSchwann cells in the CNS in pathological conditions, ... -
Slit1 Protein Regulates SVZ-Derived Precursor Mobilization in the Adult Demyelinated CNS
(Frontiers Media, 2020)Slit1 is a secreted axon guidance molecule, also involved in adult neurogenesis. In physiological conditions, Slit1 loss promotes ectopic dispersal of SVZ-derived neural precursors (SVZ-NPCs) into periventricular structures ...