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Listar por autor "Marí-Beffa, Manuel"
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Copper-containing mesoporous bioactive glass promotes angiogenesis in an in vivo zebrafish model
Romero-Sánchez, Lilian B.; Mari-Beffa, Manuel; Carrillo Fernández, Paloma; Medina-Torres, Miguel Ángel; Díaz-Cuenca, Aránzazu (2018-10-19)The osteogenic and angiogenic responses of organisms to the ionic products of degradation of bioactive glasses (BGs) are being intensively investigated. The promotion of angiogenesis by copper (Cu) has been known for more ... -
Dimethylfumarate Inhibits Angiogenesis In Vitro and In Vivo: A Possible Role for Its Antipsoriatic Effect?
García-Caballero, Melissa; Mari-Beffa, Manuel; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (Elsevier, 2011-06-02)Los ésteres de ácido fumárico (FAE) se han utilizado para el tratamiento oral de la psoriasis durante unos 50 años. Dado que una angiogénesis persistente y mantenida está asociada con varias enfermedades cutáneas, incluida ... -
El temperamento de la aventura científica: entrevista a Antonio García-Bellido
Mari-Beffa, Manuel (Universidad de Málaga, 2020) -
Fishing anti(lymph)angiogenic drugs with zebrafish
García-Caballero, Melissa; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Mari-Beffa, Manuel (2018-10-19)Zebrafish, an amenable small teleost fish with a complex mammal-like circulatory system, is being increasingly used for drug screening and toxicity studies. It combines the biological complexity of in vivo models with a ... -
In vitro and in vivo effects of ulvan polysaccharides from Ulva rigida
García-Márquez, Jorge; Rodrigues Moreira, Bruna; Valverde-Guillén, Piedad; Latorre-Redoli, Sofía; Caneda-Santiago, Candela T.; Acién-Fernández, Francisco Gabriel; Martínez-Manzanares, Eduardo; Mari-Beffa, Manuel; Abdala-Díaz, Roberto Teófilo[et al.] (MDPI, 2023-04-28)One of the main bioactive compounds of interest from the Ulva species is the sulfated polysaccharide ulvan, which has recently attracted attention for its anticancer properties. This study investigated the cytotoxic activity ... -
Novel synthetic UV screen compounds inspired in mycosporine-like amino acids (MAAs): Antioxidant capacity, photoprotective properties and toxicity
López-Figueroa, Félix; Castro Varela, Pablo Andrés; Vega, Julia; Losantos, Raúl; Peñín, Beatriz; López-Cóndor, Leonardo; Pacheco-Rodriguez, María Jesús; Latorre-Redoli, Sofía; Mari-Beffa, Manuel; Abdala-Díaz, Roberto Teófilo; Sampedro Ruiz, Diego[et al.] (Elsevier, 2024)The combination of environmental stress on the ozone layer, climate change and a greater sun exposure due to outdoor habits has led to an increase in skin cancer cases and other health issues related with UV radiation. ... -
Synthesis, characterization and biological evaluation of octyltrimethylammonium tetrathiotungstate
Vega-Granados, Karla; Cruz-Reyes, Juan; Horta-Marrón, José F.; Mari-Beffa, Manuel; Díaz-Rubio, Laura; Córdova-Guerrero, Iván; Chávez-Velasco, Daniel; Ocaña Farfán, María del Carmen; Medina-Torres, Miguel Ángel; Romero-Sánchez, Lilian B.[et al.] (Springer Nature, 2021)Octyltrimethylammonium tetrathiotungstate salt (ATT-C8) was synthesized and its ability to chelate copper was evaluated. The biological and toxic aspects were evaluated by in vitro and in vivo assays, using bovine aorta ... -
Toluquinol, a marine fungus metabolite, is a new angiosuppresor that interferes the Akt pathway.
García-Caballero, Melissa; Mari-Beffa, Manuel; Cañedo, Librada; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (Elsevier, 2013-06-15)El toluquinol, una metilhidroquinona producida por un hongo marino, fue seleccionado en el curso de una selección a ciegas de nuevos inhibidores potenciales de la angiogénesis. En el presente estudio proporcionamos la ...