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Listar por autor "Tabbai-Amal, Sara"
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The absence of LPA1 receptor results in lipidome dysregulation and Neuropeptide-Y underexpression
Tabbai-Amal, Sara; Moreno-Fernández, Román D.; Pérez-Martín, Margarita; Rosell-del-Valle, Cristina; Castilla-Ortega, María Estela; Fernández, María; Chun, Jerold; Rodriguez-de-Fonseca, Fernando; Estivill-Torrús, Guillermo; Santín-Núñez, Luis Javier; Pedraza-Benítez, María del Carmen[et al.] (2018-07-18)LPA1 receptor is one of the six characterized G protein-coupled receptors (LPA1-6) through which lysophosphatidic acid acts as an intercellular signaling molecule. It has been shown that the LPA1 receptor is involved in ... -
Acute psychological stress: effects on hippocampal neurogenesis and the role of microglia
Nieto-Quero, Andrea; Chaves-Peña, Patricia; Infantes-López, M. Inmaculada; Zambrana-Infantes, Emma; Tabbai-Amal, Sara; Muñoz-Martin, José; Pérez-Martín, Margarita; Pedraza-Benítez, María del Carmen[et al.] (2022)Among all the factors that can contribute to the onset of psychopathological disorders, stress is the main environmental factor. The hippocampus is one of the most sensitive regions to the harmful effects of stress, in ... -
Determinación de las especies de LPA en hipocampo de ratón. Efecto de diferentes protocolos de estrés
Tabbai-Amal, Sara (UMA Editorial, 2020)El LPA es un lípido bioactivo que está involucrado en la señalización intracelular a través de los seis receptores acoplados a proteínas G (LPA1-6). Entre estos receptores, LPA1 es un fuerte candidato para mediar los efectos ... -
Effects on the hippocampal microglia after acute treatment of a psychological stressor associated with depressive-like behaviours
Nieto-Quero, Andrea; Infantes-López, M. Inmaculada; Zambrana-Infantes, Emma; Chaves-Peña, Patricia; Tabbai-Amal, Sara; Pérez-Martín, Margarita; Pedraza-Benítez, María del Carmen[et al.] (2021-07)Stressful life events may have a negative impact on mental health compromising people's well-being, so knowing the neurobiological changes that occur after psychosocial stressors can have an impact on overall health. ... -
Microglial and neurogenic alterations in hypothalamus due to acute stress
Infantes-López, M. Inmaculada; Nieto-Quero, Andrea; Zambrana-Infantes, Emma; Chaves-Peña, Patricia; Tabbai-Amal, Sara; Pedraza-Benítez, María del Carmen; Pérez-Martín, Margarita[et al.] (2021-07)Microglial cells are an important glial population known to be involved in several biological processes such as stress response. These cells engage an activated state following a stress insult that may lead to nervous ... -
Stress coping behaviour, brain connectivity and LPA1 receptor: similarities and differences between the genetic and the pharmacological approach
Moreno-Fernández, Román; Nieto-Quero, Andrea; Gómez-Salas, Francisco Javier; Tabbai-Amal, Sara; García-Fernández, María Inmaculada; Chun, Jerold; Pedraza-Benítez, María del Carmen; Rosell-del-Valle, Cristina; Pérez-Martín, Margarita; Rodriguez-de-Fonseca, Fernando; Estivill-Torrús, Guillermo; Santín-Núñez, Luis Javier[et al.] (2018-07-16)LPA1 receptor is one of the six characterized G protein-coupled receptors (LPA1-6) through which lysophosphatidic acid acts as an intercellular signalling molecule. It has been recently proposed that this receptor has a ... -
The limbic brain under stress: a role for the LPA1 receptor
Moreno-Fernández, Román D.; Tabbai-Amal, Sara; Gómez-Salas, Francisco Javier; Pérez-Martín, Margarita; Rosell-del-Valle, Cristina; Castilla-Ortega, María Estela; García-Fernández, María Inmaculada; Chun, Jerold; Rodriguez-de-Fonseca, Fernando; Estivill-Torrús, Guillermo; Santín-Núñez, Luis Javier; Pedraza-Benítez, María del Carmen[et al.] (UNED, 2017-07)Adverse events can impact brain structure and function and are considered primary sources of risk for depression, anxiety, and other psychiatric disorders. In this sense, the neurobiological circuitry in charge of dealing ...