Listar por autor "Lumbreras-Vega, Luis Joaquín"
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Resistance acquisition after seven cycles of in vitro bleomycin exposure
Burgos-Molina, Antonio Manuel
; Gil-Carmona, Luisa; Lumbreras-Vega, Luis Joaquín; Ruiz-Gómez, Miguel José (2019-01-16)
Bleomycin is an antineoplastic drug that causes DNA damage by intra- and inter-strand crosslink and DNA strand breaks. This drug is used to treat several types of cancer. The aim of this work is to study the effect of ... -
Selection of resistance to cisplatin in saccharomyces cerevisiae as a model for antineoplastic drugs studies
Burgos-Molina, Antonio Manuel; Lumbreras-Vega, Luis Joaquín; Gil-Carmona, Luisa; Ruiz-Gómez, Miguel José (2019-01-16)
The budding yeast (S. cerevisiae) is an excellent eukaryotic model to study the antineoplastic drugs effects, due to the well-characterized metabolic and genetic characteristics and the conserved similarity in molecular ...