Listar por autor "López-Gambero, Antonio J."
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Dietary administration of D-chiro-inositol attenuates sex-specific metabolic imbalances in the 5xFAD mouse model of Alzheimer’s disease
López-Gambero, Antonio J.; Pacheco-Sánchez, Beatriz; Rosell-del-Valle, Cristina; Medina-Vera, Dina; Navarro, Juan Antonio; Fernández-Arjona, María del Mar; De Ceglia, Marialuisa; Sanjuán-Solís, Jesús Carlos
; Simon, Vincent; Cota, Daniela; Rivera, Patricia; Rodriguez-de-Fonseca, Fernando; Suárez-Pérez, Juan[et al.] (Elsevier, 2022-06)
Increasing evidence shows that hypothalamic dysfunction, insulin resistance, and weight loss precede and progress along with the cognitive decline in sporadic Alzheimer’s Disease (AD) with sex differences. This study aimed ... -
Endocrine and Metabolic impact of oral ingestion of a carob-pod derived natural syrup containing D-Pinitol: potential use as a novel sweetener in diabetes
Navarro, Juan Antonio; Decara, Juan; Dina, Medina; Tovar, Ruben; López-Gambero, Antonio J.; Pavón-Morón, Francisco Javier; Serrano, Antonia; De Ceglia, Marialuisa; Sanjuan, Carlos; Rodriguez-de-Fonseca, Fernando; Baixeras-Llano, Elena[et al.] (EMBO, 2022)
The use of added sugars or non-nutritive sweeteners in processed foods and soft drinks are being blamed for multiple complications associated with obesity and diabetes. High fructose content contributes to obesity and liver ... -
Plasma endocannabinoid alterations as a link in the comorbidity of Alzheimer's disease and type 2 diabetes mellitus.
López-Gambero, Antonio J.; Reyes, José Antonio; Fernández-Arjona, María del Mar; Rubio-Lamia, Leticia Olga; Rivera, Patricia; Serrano-Castro, Pedro Jesús; Rodriguez-de-Fonseca, Fernando; Suárez-Pérez, Juan[et al.] (2023)
Over the last several years, studies have suggested a role of endocannabinoids such as 2-AG and 2-OG in the impairment of β-cell function and insulin secretion, as well as in the control of lipid and glucose metabolism in ... -
Plasma endocannabinoids as potential biomarkers of type 2 diabetes mellitus in elderly patients with mild cognitive impairment
López-Gambero, Antonio J.; Reyes, José Antonio; Fernández-Arjona, María del Mar; Rubio-Lamia, Leticia Olga; Rivera, Patricia; Serrano-Castro, Pedro Jesús; Rodriguez-de-Fonseca, Fernando; Suárez-Pérez, Juan[et al.] (Sociedad Española de Investigación sobre Cannabinoides (SEIC), 2022)
Background: Besides their role in the nervous system and the development of cognitive impairment in elderly patients, compelling evidence suggests that endocannabinoids (ECBs) are related to motivational responses in obesity ... -
Recombinant IGF-1 Induces Sex-Specific Changes in Bone Composition and Remodeling in Adult Mice with Pappa2 Deficiency
Rubio-Lamia, Leticia Olga; Vargas, Antonio; River, Patricia; López-Gambero, Antonio J.; Tobar, Rubén; Christians, Julian K.; Martín-de-las-Heras, Stella; Rodriguez-de-Fonseca, Fernando; Chowen, Julie A.; Argente, Jesús; Suárez-Pérez, Juan[et al.] (MDPI, 2021)
Deficiency of pregnancy-associated plasma protein-A2 (PAPP-A2), an IGF-1 availability regulator, causes postnatal growth failure and dysregulation of bone size and density. The present study aimed to determine the effects ... -
Sex-based differences in growth-related IGF1 signaling in response to PAPP-A2 deficiency: comparative effects of rhGH, rhIGF1 and rhPAPP-A2 treatments
Fernández-Arjona, María del Mar; Navarro, Juan Antonio; López-Gambero, Antonio J.; De Ceglia, Marialuisa; Rodríguez, Miguel; Rubio-Lamia, Leticia Olga; Rodríguez de Fonseca, Fernando; Barrios, Vicente; Chowen, Julie A.; Argente, Jesús; Rivera, Patricia; Suárez-Pérez, Juan[et al.] (BMC Springer Nature, 2024-04-08)
Understanding the physiological role of pregnancy-associated plasma protein-A2 (PAPP-A2), a proteinase involved in the insulin-like growth factor-1 (IGF1) availability to regulate growth, could provide insight into new ...