Listar por autor "Pérez-Cano, Ana María"
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Effects of sequential exposure to physical exercise and cognitive training on hippocampal neurogenesis in mice
Ávila-Gámiz, Fabiola; Pérez-Cano, Ana María; Mullor-Vigo, Rosa; Pérez-Berlanga, José Manuel; Zambrana-Infantes, Emma; Santín-Núñez, Luis Javier
; Ladrón de Guevara-Miranda, David[et al.] (2022-07-13)
AIMS: Physical exercise and cognitive training hippocampal dependent tasks are known to enhance adult hippocampal neurogenesis (AHN). Here we aimed to evaluate the effect of either a moderate-intensity exercise protocol, ... -
Neuroprotective effects of insulin-like growth factor II in a mouse model of Parkinson's disease
Ladrón de Guevara-Miranda, David; Martín-Montañez, Elisa; Valverde, Nadia; Lara, Estrella; Romero-Zerbo, Silvana Yanina; Millón-Peñuela, Carmelo; Boraldi, Federica; Ávila-Gámiz, Fabiola; Pérez-Cano, Ana María; Garrido-Gil, Pablo; Labandeira-García, José Luis; Santín-Núñez, Luis Javier; Pavía-Molina, José; García-Fernández, María Inmaculada[et al.] (2022-07-20)
Progressive degeneration of the nigrostriatal dopaminergic pathway is a core, currently irreversible pathological hallmark of Parkinson’s disease (PD) that leads to a variety of motor and non-motor symptoms. Here, we aimed ... -
Pharmacogenetic inhibition of the infralimbic cortex promotes reinstatement of cocaine-context memories in mice.
Pérez-Cano, Ana María; Ávila-Gámiz, Fabiola; Pérez Berlanga, José Manuel; Santín-Núñez, Luis Javier; Ladrón de Guevara-Miranda, David (2023)
Relapse is one of the main problems concerning treatment of cocaine use disorder. It have been suggested that the infralimbic cortex (IL), a division of the medial prefrontal cortex, is involved in extinction and reinstatement ... -
Selective modulation of the infralimbic cortex activity regulates reinstatement of cocaine-context associations in mice.
Pérez-Cano, Ana María; Pérez-Berlanga, José Manuel; Ávila-Gámiz, Fabiola; Santín-Núñez, Luis Javier; Ladrón de Guevara-Miranda, David (2024)
Mechanisms underlying relapse into cocaine are not yet fully understood. Animal studies suggest a pivotal involvement of the infralimbic (IL) division of the medial prefrontal cortex, but causal evidence is lacking. Here, ... -
Sequential physical and cognitive training disrupts cocaine-context associations via multi-level stimulation of adult hippocampal neurogenesis
Ávila-Gámiz, Fabiola; Pérez-Cano, Ana M.; Pérez-Berlanga, José Manuel; Zambrana-Infantes, Emma N.; Mañas-Padilla, M. Carmen; Gil-Rodríguez, Sara; Tronel, Sophie; Santín-Núñez, Luis Javier; Ladrón de Guevara-Miranda, David[et al.] (Elsevier, 2025-01-10)
Cocaine-related contextual cues are a recurrent source of craving and relapse. Extinction of cue-driven cocaine seeking remains a clinical challenge, and the search for adjuvants is ongoing. In this regard, combining ... -
Sequential treadmill exercise and cognitive training synergistically increase adult hippocampal neurogenesis in mice
Ávila-Gámiz, Fabiola; Pérez-Cano, Ana María; Pérez-Berlanga, José Manuel; Mullor-Vigo, Rosa; Zambrana-Infantes, Emma; Santín-Núñez, Luis Javier; Ladrón de Guevara-Miranda, David[et al.] (Elsevier, 2023)
Combining physical and cognitive training has been suggested to promote further benefits on brain and cognition, which could include synergistic improvement of hippocampal neuroplasticity. In this paper, we investigated ... -
The infralimbic cortex and the hippocampal CA1-Subiculum are functionally involved in the extinction of cocaine-context associationes in mice.
Pérez Berlanga, José Manuel; Ávila-Gámiz, Fabiola; Pérez-Cano, Ana María; Mullor-Vigo, Rosa; Santín-Núñez, Luis Javier; Ladrón de Guevara-Miranda, David[et al.] (2023)
Cocaine abuse is a health and social problem worldwide. Treatment seeking for cocaine use disorder is on the rise, and relapse prevention remains as a primary goal. Interventions based on extinction of cocaine-related ...