Listar por autor "Rodriguez-Ortiz, Carlos"
Mostrando ítems 1-4 de 4
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Amyloid-beta impairs TOM1-mediated IL-1R1 signaling
Cadete Martini, Alessandra; Gomez-Arboledas, Angela; Forner, Stefania; Rodriguez-Ortiz, Carlos; McQuade, Amanda; Danhash, Emma; Phan, Jimmy; Javoncillo, Dominic; Ha, Jordan-Vu; Tram, Melanie; Trujillo-Estrada, Laura Isabel
; da Cunha, Celia; Ager, Rahasson; Davila, Jose Carlos; Kitazawa, Masashi; Blurton-Jones, Mathew; Gutierrez, Antonia; Baglietto-Vargas, David; Medeiros, Rodrigo; LaFerla, Frank M[et al.] (National Academy of Sciences, 2019-10)
Defects in interleukin-1β (IL-1β)-mediated cellular responses contribute to Alzheimer's disease (AD). To decipher the mechanism associated with its pathogenesis, we investigated the molecular events associated with the ... -
Impact of white adipose tissue in AD pathology
Bettinetti-Luque, Miriam; Trujillo-Estrada, Laura Isabel; Andreo-López, Juana; Cantero-Molina, Francisco; Rodriguez-Ortiz, Carlos J; LaFerla, Frank; Gutiérrez-Pérez, Antonia; Baglietto-Vargas, David[et al.] (2022)
Aims: Alzheimer’s disease (AD) is a complex disorder and multiple cellular and molecular mechanisms are involved in AD onset and progression. Recent evidences has suggested that metabolic alterations are an important ... -
Impact of white adipose tissue in AD pathology
Bettinetti-Luque, Miriam; Andreo-López, Juana; Cantero-Molina, Francisco; Trujillo-Estrada, Laura Isabel; Rodriguez-Ortiz, Carlos J; LaFerla, Frank; Gutiérrez-Pérez, Antonia; Baglietto-Vargas, David[et al.] (2021-11-04)
Introduction: Alzheimer’s disease (AD) is a complex disorder and multiple cellular and molecular mechanisms are involved in AD onset and progression. Recent evidences has suggested that metabolic alterations are an important ... -
Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus
Forner, Stefania; Martini, Alessandra; Prieto, Gilberto Aleph; Dang, Cindy; Rodriguez-Ortiz, Carlos; Reyes Ruiz, Jorge Mauricio; Trujillo-Estrada, Laura Isabel; da Cunha, Celia; Andrews, Elizabeth; Phan, Jimmy; Ha, Jordan; Chang, Allissa; Levites, Yona; Cruz, Pedro; Ager, Rahasson; Medeiros, Rodrigo; Kitazawa, Masashi; Glabe, Charles; Cotman, Carl; Golde, Todd; Baglietto-Vargas, David; LaFerla, Frank M[et al.] (Springer Nature, 2019-11)
Alzheimer's disease (AD), the most common age-related neurodegenerative disorder, is currently conceptualized as a disease of synaptic failure. Synaptic impairments are robust within the AD brain and better correlate with ...