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Listar por autor "Medina, Miguel Ángel"
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Exploring and challenging the network of angiogenesis
Montañez, Raúl; Sánchez-Jiménez, Francisca María; Medina, Miguel Ángel; Rodríguez-Quesada, Ana María (Springer Nature, 2011-08-11)Angiogenesis is one of the hallmarks of cancer and, as such, one of the alternative general targets for anticancer therapy. Since angiogenesis is a complex process involving a high number of interconnected components, a ... -
Synthesis and Antitumor Activity Evaluation of Compounds Based on Toluquinol
Cheng-Sánchez, Iván; Torres-Vargas, José Antonio; Martínez-Póveda, Beatriz Amparo; Guerrero Vásquez, Guillermo A.; Medina, Miguel Ángel; Sarabia-García, Francisco Ramón; Quesada, Ana R.[et al.] (MDPI, 2019-08-23)Encouraged by the promising antitumoral, antiangiogenic, and antilymphangiogenic properties of toluquinol, a set of analogues of this natural product of marine origin was synthesized to explore and evaluate the effects of ... -
VUS next in rare diseases? Deciphering genetic determinants of biomolecular condensation
Heredia-Torrejón, María; Montañez, Raúl; González-Menese, Antonio; Carcavilla, Atilano; Lechuga-Sancho, Alfonso María; Medina, Miguel Ángel[et al.] (BioMed Central, 2024-09-06)The diagnostic odysseys for rare disease patients are getting shorter as next-generation sequencing becomes more widespread. However, the complex genetic diversity and factors influencing expressivity continue to challenge ...