Listar por autor "Da Cunha, Celia"
Mostrando ítems 1-9 de 9
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Amyloid propagation in a sporadic model of Alzheimer disease
Andreo-López, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Huynh, Kelly; Nguyen, Marie; Cheung, Alwin; Tran, Janine; Da Cunha, Celia; Trujillo-Estrada, Laura Isabel
; Nuñez-Diaz, Cristina; Cadete-Martini, Alessandra; Forner, Stefania; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (2021-11-04)
Most age-associated neurodegenerative disorders involve the aggregation of specific proteins within the nervous system, as occurs in Alzheimer’s disease (AD). Recent evidence indicates that Aβ can misfold and aggregate ... -
Amyloid-b seeding and propagation processes in a hAb-KI model of Alzheimer's disease
Trujillo-Estrada, Laura Isabel; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Cheung, Alwin; Pham Tran, Janine; Nunez-Diaz, Cristina; Forner, Stefania; Martini, Alessandra; Da Cunha, Celia; Shahnawaz, Mohammad; Soto, Claudio; Moreno-Gonzalez, Ines; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (2020-12-17)
Recent evidence indicates that Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like process. Several studies using FAD animal models have demonstrated that ... -
Amyloid-β seeding and propagation processes in a hAβ-KI model of Alzheimer's disease
Trujillo-Estrada, Laura Isabel; Minh Thu Nguyen, Marie; Baglietto-Vargas, David; LaFerla, Frank; Gutiérrez-Pérez, Antonia; Moreno-Gonzalez, Ines; Soto, Claudio; Shahnawaz, Mohammad; Da Cunha, Celia; Forner, Stefania; Nunez-Diaz, Cristina; Pham Tran, Janine; Cheung, Alwin; Do Huynh, Kelly; Martinie, Alessandra C.[et al.] (Cold Spring Harbor Laboratory, 2020-12-02)
Recent evidence indicates that Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like process. Several studies using FAD animal models have demonstrated that ... -
Human amyloid seeds aggregate more efficient than seeds from old 3xtg-ad mice
Andreo-López, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Huynh, Kelly; Thu Nguyen, Marie Minh; Cheung, Alwin; Tran, Janine Pham; Da Cunha, Celia; Trujillo-Estrada, Laura Isabel; Nuñez-Diaz, Cristina; Cadete-Martini, Alessandra; Forner, Stefania; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (2022)
Aims: Most age-associated neurodegenerative disorders involve the aggregation of specific proteins within the nervous system, as occurs in Alzheimer’s disease (AD). Recent evidence indicates that Aβ can misfold and aggregate ... -
Human and mouse seeds differentially affect AB aggregation by modulating the inflammatory response.
Andreo-López, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Cheung, Alwin; Pham Tran, Janine; Da Cunha, Celia; Morales-Cabello, Mario; Fatuarte Juli, Ivan; Trujillo-Estrada, Laura Isabel; Núñez Díaz, Cristina; Cadete-Martini, Alessandra; Forner, Stefania; LaFerla, Frank; Gutiérrez-Pérez, Antonia; Baglietto-Vargas, David[et al.] (2023)
Abstract text: Alzheimer’s Disease (AD) is a neurodegenerative proteinopathy in which Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prionlike process. These amyloid aggregation ... -
Human and mouse seeds differentially affect Aβ aggregation by modulating the inflammatory response
Andreo-López, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Cheung, Alwin; Pham Tran, Janine; Da Cunha, Celia; Trujillo-Estrada, Laura Isabel; Nuñez Diaz, Cristina; Cadete-Martini, Alessandra; Forner, Stefania; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (2023)
Background: Alzheimer’s Disease (AD) is a neurodegenerative proteinopathy in which Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like process. These amyloid aggregation ... -
Visceral adipose tissue triggers tau pathogenesis in transgenic mice
Bettinetti-Luque, Miriam; Trujillo-Estrada, Laura Isabel; Andreo-López, Juana; Cantero-Molina, Francisco; Da Cunha, Celia; Sánchez-Mejías, Elisabet; LaFerla, Frank; Gutiérrez-Pérez, Antonia; Baglietto-Vargas, David[et al.] (2023-07-19)
Alzheimer’s disease (AD) is a complex disorder and multiple cellular and molecular mechanisms are involved in AD onset and progression. Recent evidences have suggested that metabolic alterations are an important pathological ... -
Visceral adipose tissue triggers tau pathogenesis in transgenic mice through CDK5/P25 pathway.
Bettinetti-Luque, Miriam; Trujillo-Estrada, Laura Isabel; Andreo-López, Juana; Campos-Moreno, Cynthia; Fatuarte Juli, Ivan; Morales-Cabello, Mario; Da Cunha, Celia; Sánchez-Mejías, Elisabet; LaFerla, Frank; Gutiérrez-Pérez, Antonia; Baglietto-Vargas, David[et al.] (2023)
Alzheimer’s disease (AD) is a complex disorder and multiple molecular mechanisms are involved in AD onset and progression. Recent evidences have suggested that metabolic alterations are an important pathological feature ... -
WAT alterations in diabetic mice: its connection and implication in ad pathogenesis.
Bettinetti-Luque, Miriam; Trujillo-Estrada, Laura Isabel; Andreo-López, Juana; Cantero-Molina, Francisco; Da Cunha, Celia; Sánchez-Mejías, Elisabet; LaFerla, Frank; Gutiérrez-Pérez, Antonia; Baglietto-Vargas, David[et al.] (2022-07-13)
Alzheimer’s disease (AD) is a complex disorder and multiple cellular and molecular mechanisms are involved in AD onset and progression. Recent evidences have suggested that metabolic alterations are an important pathological ...